Leqvio, the cholesterol vaccine
High cholesterol is one of the main risk factors for cardiovascular diseases, which are the leading cause of death in the world. Although there are effective medications to lower cholesterol, such as statins, many patients fail to reach recommended levels or experience side effects. Therefore, the search for new therapeutic alternatives is a priority for public health Leqvio, the cholesterol vaccine One of the most innovative and promising options is Leqvio, a vaccine that acts on the PCSK9 gene, responsible for regulating blood cholesterol levels. PCSK9 binds to low-density lipoprotein (LDL) receptors, which are responsible for transporting cholesterol from the liver to the cells. By doing so, it prevents receptors from recycling cholesterol and removing it from the body, causing it to build up in the arteries and increasing the risk of heart attack or stroke. Leqvio is a treatment based on messenger RNA (mRNA), the same one used in some of the vaccines against ...